India Mcqs

Pharmacology

Only Aspirin can:

A. Reduce fever.
B. Irreversible inhibit its target enzyme.
C. Prevent episodes of gouty arthritis with long term use.
D. Reduce the risk of colon cancer.

Which of the following statements concerning potassium channel openers is true?

A. These agents decrease transmembrane calcium current associated in a smooth muscle with long-lasting relaxation
and in a cardiac muscle with a reduction in contractility
B. These agents has a moderate reflex and vascular dilative action caused by the stimulation of sensitive nerve endings
C. Beneficial effects of these agents are related primarily to their hemodynamic effects – decreased heart rate, blood
pressure, and contractility – which decrease myocardial oxygen requirements at rest and during exercise
D. These agents increase the permeability of K channels, probably ATP-dependent K channels, that results in stabilizing the membrane potential of excitable cells near the resting potential

Tick the feature of the sublingual route:

A. Pretty fast absorption
B. A drug is exposed to gastric secretion
C. A drug is exposed more prominent liver metabolism
D. A drug can be administrated in a variety of doses